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URINE DRUG ANALYSIS

Drug analysis samples can be submitted in the gray stoppered tubes used for alcohol analysis, and/or bottles, containers, or equivalent.

The detection of drugs in a urine sample is determined by initial screening or presumptive tests.  These tests target compounds in a drug group rather than specific drugs.  Following a positive screening result on a sample, a second confirmatory test is performed.  This second test uses a different analytical technique to identify a specific drug compound. 

Randox Screening Drugs & Levels:

The “Screening of Drugs” lists the drug categories for DOA1+ & DOAV screening panels.  DOA1+ testing is performed on all urine samples requesting drug screen analysis (pre-log: TXUD).  Depending on specific agency requests, DOAV testing may be completed.  DOA1+ and DOAV panels are completed using a Randox Instrument.

 

Randox Screening Levels – DOA1+ (Urine Samples)

Drug Group:

2017

2016

2015

Total Amphetamines
Amphetamine & Methamphetamine

≥ 595

≥ 596

≥ 589

Barbiturates

≥ 100

≥ 100

≥ 100

Benzodiazepines I

≥ 50

≥ 50

≥ 50

Benzodiazepines II

≥ 20

≥ 50

≥ 50

Methadone

≥ 150

≥ 150

≥ 150

Opiates

≥ 2247

≥ 2381

≥ 2381

Cocaine Metabolites

≥ 177

≥ 181

≥ 177

MDMA

≥ 602

≥ 610

≥ 618

Marijuana Metabolites

≥ 60

≥ 62.5

≥ 62

Tricyclics

≥ 50

≥ 50

≥ 50

Buprenorphine

≥ 5

≥ 5

≥ 5

PCP

≥ 32

≥ 32

≥ 32


Confirmation of Drug Categories (Confirmations):


When a screening test is positive, a confirmatory test is performed to identify the drug.  “Confirmation of Drug Categories” lists drug compounds that are typically reported following this second, confirmatory test.

Amphetamines Confirmation (Urine Samples):

amphetamine

methamphetamine

3,4-methylenedioxyamphetamine (MDA)

3,4-methylenedioxymethamphetamine (MDMA)

Phentermine

Barbituates Confirmation (Urine Samples):

butalbital

secobarbital

butabarbital

amobarbital

hexobarbital

phenobarbital

Opiates Confirmation (Urine Samples):

6-MAM

buprenorphine

codeine

dihydrocodeine

fentanyl

hydrocodone

hydromorphone

meperidine

methadone

morphine

norbuprenorphine

norcodeine

norfentanyl

normorphine

oxycodone

oxymorphone

propoxyphene


Cannabinoids Confirmation (Urine Samples) :

Common Name:

11-nor-9-carbody-delta-9-tetrahydrocannabinol

metabolite of THC

Cocaine Confirmation (Urine Samples) :

Common Name:

benzolyecgonine

metabolite of cocaine

cocaine

---

ecgonine methyl ester

metabolite of cocaine

ethylbenzoylecgonine

Cocaethylene, a metabolite of cocaine

Benzodiazepines & Sleep Drugs (Urine Samples):

Common Name:

7-aminoclonazepam

metabolite of clonazepam

7-aminoflurazepam

metabolite of flurazepam

alphahydroxyalprazolam

alprazolam metabolite

alphahydroxymidazolam

metabolite of midazolam

alphahydroxytriazolam

metabolite of triazolam

alprazolam

Xanax

bromazepam

 

chlordiazepoxide

librium

clonazepam

Klonopin

desalkyflurazepam

metabolite of flurazepam

diazepam

Valium

estazolam

 

flunitrazepam

rohypnol

flurazepam

dalmane

halazepam

 

hydroxyethylflurazepam

metabolite of flurazepam

lorazepam

Activan

midazolam

versed

nordiazepam

metabolite of diazepam, chloradiazepoxide & halazepam

oxazepam

also a metabolite of temazepam & diazepam

temazepam

also a metabolite of diazepam

traizolam

halcion

zolpiclone

lunesta

zopidem

ambien



Target Compounds:

“Target compounds” provides a list of drugs for a special type of screening method employing an instrument called the LCMSMS.  Rather than drug categories, it focuses on drug compounds.  This screening test is used in cases of Drug Facilitated Sexual Assault and other toxicology cases with special drug requests and cases that require additional information for confirmation testing. 

Target Drugs Tested for in Toxicology (Urine Samples):    Last Updated: February 2017

1

2CB

70

Ethenzamide

139

Nitrazepam

2

2-oro-3-hydroxy LSD

71

Fenspiride

140

Norbuprenorphine

3

4-MePPP

72

Fentanyl

141

Norclomipramine

4

4-chloro-2,5-dimethoxyamphetamine (DOC)

73

Flecainide

142

Nordiazepam

5

5-methoxy-DALT

74

Flumazenil

143

Nordoxepin

6

6MAM

75

Flunitrazepam

144

Norfentanyl

7

7-aminoclonazepam

76

Fluoxetine

145

Norfluoxetine

8

7-aminoflunitrazepam

77

Fluphenazine

146

Norketamine

9

7-hydroxyquetiapine

78

Flurazepam

147

Normeperidine

10

4-fluormethamphetamine

79

Fluvoxamine

148

Norpropoxyphene

11

Acebutolol

80

Gabapentin

149

Norquetiapine

12

Acetylfentanyl

81

Haloperidol

150

Nortriptyline

13

alpha-PVP

82

Heroin

151

Norverapamil

14

Alprazolam

83

Hydrocodone

152

O-desmethylvenlafaxine

15

Amiodarone

84

Hydromorphone

153

Olanzapine

16

Amitriptylene

85

Hydroquinidine

154

Orphenadrine

17

Amoxapine

86

Hydroxyalprazolam

155

Oxazepam

18

Amphetamine

87

Hydroxyzine

156

Oxcarbazepine

19

Atenolol

88

Imipramine

157

Oxprenolol

20

Atropine

89

Indomethazin

158

Oxycodone

21

Benzoylecgonine

90

Isometheptene

159

Paracetamol

22

Benzylpiperazine

91

25-I-NBoMe

160

Paroxetine

23

Betaxolol

92

Ketamine

161

PCP

24

Bisoprolol

93

Labetolol

162

Pentadrone

25

Bromazepam

94

Lamotrigine

163

Perphenazine

26

Brompheniramine

95

Lidocaine

164

Pheniramine

27

Bupivacaine

96

Loprazolam

165

Phenothiazine(2)

28

Buprenorphine

97

Lorazepam

166

Phenotiazine (1)

29

Bupropion

98

Lormetazepam

167

Phenylpropanolamine (PPA)

30

Bupropion hydroxyl metabolite

99

Loxapine

168

Phenytoin

31

Butorphanol

100

LSD

169

Pindolol

32

Caffeine

101

Maprotiline

170

Piroxicam

33

Carbamazepine

102

MBDB

171

Prazepam

34

Carbamazepine 10,11 epoxide

103

mCPP

172

Primidone

35

Carisoprodol

104

MDA

173

Procaine

36

Cathine

105

MDEA

174

Promethazine

37

Cathinone

106

MDMA

175

Propafenone

38

Chlordiazepoxide

107

MDPV

176

Propanolol

39

Chloroquine

108

Meloxicam

177

Propoxyphene

40

Chlorpheniramine

109

Meperidine

178

Pseudoephedrine

41

Chlorpromazine

110

Mephedrone

179

Quetiapine

42

Citalopram

111

Meprobamate

180

Quinidine

43

Clenbuterol

112

Mescaline

181

Reserpine

44

Clobazam

113

Methadone

182

Risperidone

45

Clomipramine

114

Methamphetamine

183

Salbutamol

46

Clonazepam

115

Methaqualone

184

Scopolamine

47

Clonidine

116

Methedrone

185

Sertraline

48

Clozapine

117

Methocarbamol

186

Strychnine

49

Cocaine

118

Methyl Clonazepam

187

Sundilac

50

Codeine

119

Methylhexanamine

188

Tapentaldol

51

Colchicine

120

Methylphenidate

189

Temazepam

52

Cyclobenzaprine

121

Metoclopramide

190

Tetracaine

53

Desalkyl flurazepam

122

Metoprolol

191

Tetrazepam

54

Desipramine

123

Mianserine

192

TFMPP

55

Desmethylcyclobenzaprine

124

Midazolam

193

Theophylline

56

Dextromethorphan

125

Milnacipran

194

Thioridazine

57

Dextrorphan

126

Mitragynine

195

Tiapride

58

Diazepam

127

Mirtazepine

196

Topiramate

59

Dihydrocodeine

128

Modafinil

197

Tramadol

60

Diltiazem

129

Molsidomine

198

Trazadone

61

Diphenhydramine

130

Morphine

199

Triazolam

62

Disopyramide

131

Nadolol

200

Trifluoperazine

63

Doxepin

132

Nalbuphine

201

Trimipramine

64

Doxylamine

133

Nalorphine

202

Tripolidine

65

Droperidol

134

Naltrexone

203

Venlafaxine

66

Duloxetine

135

Naphazoline

204

Verapamil

67

EDDP

136

Naproxen

205

Zolpidem

68

Ephedrine

137

n-desmethyltramadol

206

Zopiclone

69

Estazolam

138

Nicotine

 

 

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